PTN, MK, PVRL4, EPHA2, TFPI-2, hK11, SYND1, ANGPT2 and hK14 were found elevated in the metastatic disease when compared to cancer-free, CPG1 and/or CPG5 groups (Fig. 1b, c and Supplementary Fig. S1). This evidence concerns the gene TFPI2 and metastatic neoplasm.