LPXN and coronary artery disorder: We also explored the potential association between the plasma biomarkers and family history of CAD (Supplementary Table 5) and found significant correlations between LP-IR (β = 0.20, p = 1.18 × 10−17), LDLP (β = 0.07, p = 0.002) and HMSP (β = 0.12, p = 7.49 × 10−7) in the overall cohort.