ATOH7 and Anophthalmia: Clinically, these forms of integrative multi-system analyses will undoubtedly influence our understanding of how early human RGC loss in conditions such as anophthalmia, primary congenital glaucoma (Wilson and Di Polo, 2012) and Atoh7 loss-of-function (Prasov et al., 2012; Atac et al., 2019) influence visual system development and behavior beyond conscious vision.