Dermatological AEs were also statistically significantly increased in FLT3 inhibitor group versus control group (RR = 1.55, 95% CI 1.28 to 1.87, p < 0.00001, I2 = 36%, Supplementary Figure 13) including all subgroups (alopecia p = 0.04, hand-foot-skin reaction p = 0.01, and rash, desquamation, petechiae, itching p = 0.0005). This evidence concerns the gene FLT3 and alopecia.