FLT3 and Hypertension: Statistically significant increases were seen in vascular AEs overall with use of FLT3 inhibitors (RR = 1.52, 95% CI 1.05 to 2.19, p = 0.02, I2 = 0%, Supplementary Figure 12) though individual vascular AEs (e.g. cardiac event, hypertension, etc.)were no different between FLT3 inhibitor and control groups.