GRWD1 and breast cancer: When we looked at the genes affected by GRWD1 KD, we found a significant overlap between UMUC3 and J82 (P < 2.2e−16) but not between the BC cells and HepG2 (P > 0.4), consistent with cell-type-specific interactions and functions of circRNAs and RBPs (Additional file 8: Fig. S6I).