In NB tumors, a few possible agents have been tested in vitro and in vivo, including TNF-related apoptosis-inducing ligand (TRAIL) [191], interferon-gamma (IFN-γ) [192], IFN-β [193], and the neuronal differentiation-associated microRNA miR-124 [194]. This evidence concerns the gene IFNB1 and neuroblastoma.