Zhang et al. reported that the expression of the excitatory amino acid transporter 2 (EAAT2), the major glutamate transporter in the mammalian brain was upregulated, which is consistent with studies of postmortal brain samples from patients with depression [142,146] and the biological basis of the learned helplessness theory of depression [147]. The gene discussed is SLC1A2; the disease is depressive symptom measurement.