To investigate how tumor development influences hematological parameters in mice of different HO-1 genotypes, blood samples were collected three weeks after intravenous inoculation with B16(F10)(EGFP-I-Luc) melanoma cells and WBC, PLT, RBC, MCV, HGB, MCH, MCHC and HCT were measured using an ABC Vet® analyzer. Here, HMOX1 is linked to neoplasm.