The most well-characterized LncRNAs whose transcription were directly modulated by NRF2 include SCAL1 (LUCAT1), nuclear smoke- and cancer-associated lncRNA (NLUCAT1), NmrA-like redox sensor 2 pseudogene (NMRAL2P), Taurine-upregulated gene 1 (TUG1), and long intergenic nonprotein coding RNA 942 (LINC00942) and are listed in Table 1. The gene discussed is TUG1; the disease is cancer.