AR and posterior cortical atrophy: Furthermore, Choi et al. [93] discovered that gene silence of Bcl-2, survivin, and androgen receptor with siRNAs, which are encapsulated in pluronic F-68 polymer, along with treatment with benzethonium chloride, triggers apoptosis of human PCa LNCaP-LN3 cells more efficiently in comparison with the silencing of individual gene, suggesting that multiple gene-targeting siRNA/drug delivery system could be a feasible and promising way to combat PCa [93].