TNF and asthma: Nevertheless, studies have shown that 1,8-cineole (eucalyptol) presented anti-inflammatory and mucolytic effects in a murine model of asthma, by inhibiting the production of cytokines such as TNF-α, IL-1β, IL-4 and IL-5 by lymphocytes, as well as by inhibiting the secretion of TNF-α, IL-1β, IL-6 and IL-8 by peripheral blood mononuclear cells [45].