CDKN2BAS located in chromosome 9p21, and it is associated with a variety of human diseases, including glioma, prostate cancer, stomach cancer, pancreatic cancer, leukemia, colorectal cancer, lung cancer, diabetes, and aneurysm.[2,3] Recently, the studies of GWAS in Asian and Caucasian population identified several CDKN2BAS single-nucleotide polymorphisms (SNPs) associated with intracranial aneurysm. The gene discussed is CDKN2B-AS1; the disease is Familial prostate cancer.