To assess the differences in allele frequencies that drive the LD patterns in the tumor and normal tissues, we made separate D’ LD plots of the PARP1 gene for the lung tumor tissue samples and lung normal tissue samples to examine the differences in the LD pattern of PARP1 SNPs between lung tumor (block size: 12 kilobase-pair) and normal tissues (block size: 32 kilobase-pair) (S3 and S4 Figs in S1 File). Here, PARP1 is linked to neoplasm.