Likewise, LTBI was associated with a lower hazard of oral hairy leukoplakia (Fig 5B) when compared to MTB uninfected patients: The hazard ratios in the 3 tested models (no correction for CD4 cell count, time-updated inclusion of CD4 cell counts as continuous variable, inclusion of CD4 cell counts as categorical variable) were 0.26 [0.17, 0.40], 0.36 [0.23, 0.56], and 0.36 [0.24, 0.56], respectively, and 0.44 [0.28, 0.68], 0.61 [0.39, 0.94], and 0.59 [0.38, 0.92] after additional correction for HIV transmission group and gender, region, and HIV diagnosis year. This evidence concerns the gene CD4 and Leukoplakia, Hairy.