The emerging imaging methods, such as 11C-choline PET/CT scans, 68Ga-labelled prostate-specific membrane antigen (PSMA), Sodium Flouride (NaF) PET scan, and whole-body MRI, are more sensitive to staging PCa as these methods detect metastasis earlier than conventional methods (12, 13). This evidence concerns the gene FOLH1 and posterior cortical atrophy.