In the analysis adjusted for gender, age at screening, regimen at screening and CD4 cell count, regimen and age at ART initiation, positive full screen for depression (aOR 2.39, 95% CI 1.02 to 5.62), PTSD (aOR 3.18, 95% CI 1.11 to 9.07), substance use (aOR 7.13, 95% CI 1.60 to 31.86) or any condition (aOR 2.17, 95% CI 1.17 to 4.02) remained associated with higher odds of unsuppressed viral load (Figure 2). This evidence concerns the gene CD4 and post-traumatic stress disorder.