DNMT1 and systemic lupus erythematosus: Interestingly, both the mRNA and protein (0.40 ± 0.16 vs. 0.88 ± 0.27, P = 0.0098) levels of DNMT1 of SLE PBMC were significantly raised (Figures 2(e)–2(g)) after the coculture with BM-MSC for 4 days.