Additionally, a well-characterized single nucleotide polymorphism of OGG1 (serine 326 to cysteine) is associated with a higher risk of developing a number of different cancers (Karahalil et al., 2012), due to deficiencies in the repair of 8-oxoguanine (Bravard et al., 2009; Kershaw and Hodges, 2012). The gene discussed is OGG1; the disease is cancer.