While germline BRCA1/2 mutations occur in 5.3% of unselected breast cancers according to The Cancer Genome Atlas (TCGA), a recent study showed that 11.2% of unselected TNBC cases had deletions in the BRCA1 (8.5%) and BRCA2 (2.7%) respectively (71). This evidence concerns the gene BRCA2 and breast cancer.