(146) who used droplet digital (ddPCR) of circulating free DNA (cfDNA) to determine the PIK3CA mutation status of 49 patients with early-stage TNBC revealed that PIK3CA mutations are associated with relapse-free survival and breast cancer-specific survival and observed that PIK3CA mutations in TNBC are related to androgen receptor phosphorylation, which is known to be an independent prognostic factor for TNBC. This evidence concerns the gene PIK3CA and breast carcinoma.