As the TCGA data shows, the mRNA level of the MTA family, containing MTA1, MTA2 and MTA3, is higher in breast tumor tissues than in normal tissues (p=1e-12 in MTA1, p=9.7e-9 in MTA2, p<2.22e-16 in MTA3; Figures 1A, E, I). Here, MTA1 is linked to breast neoplasm.