CELF2 (CUGBP Elav-like family member 2) is a tumor suppressor that encodes CELF2, a protein that is one of the six-member CELF family of proteins that are recognized for their wide-ranging function in regulating pre-mRNA splicing and controlling the translation and stability of mRNAs [23]. The gene discussed is CEBPD; the disease is neoplasm.