On myogenesis, epicatechin promoted muscle differentiation by upregulating the protein expression of myogenic markers, such as MyoD, myogenin, and MHC in C2C12 muscle cells, MyoD-transfected 10T/C embryonic fibroblasts, and human rhabdomyosarcoma cells (Lee et al., 2017a). Here, MYOD1 is linked to rhabdomyosarcoma.