Using this more‐focused approach, IFN‐γ‐producing CD4+ T cells were evident in the spleen at day 3 of infection (Figure 5a), but by day 8, the YFP+ CD4+ T cells were diminished, and by day 11, the remaining YFP+ CD4+ cells in the spleen were also CD4high (Figure 5a and b). Here, CD4 is linked to infection.