We previously identified a significant positive correlation between the frequency of CD4+ T cells expressing normal levels of CD4 and increased levels of CD38 (CD4+CD38hi cells) and control of parasite growth during the first seven days of primary Plasmodium blood‐stage infection in malaria‐naïve volunteers, using a controlled human malaria infection (CHMI) model.8 The gene discussed is CD4; the disease is malaria.