More importantly, in a multivariate Cox model, we demonstrated that the ZNF667-AS1 expression was an independent poor prognostic factor for both 5-year OS (HR = 2.897, 95% CI: 1.365-4.784, p = 0.008) and 5-year DFS (HR = 3.019, CI =1.414-4.899, p = 0.005) in glioma (Table 2). The gene discussed is ZNF667; the disease is central nervous system cancer.