RAMP2 and chondrosarcoma: Furthermore, it has been reported that exosomes derived from chondrosarcoma cells carry the lncRNA receptor activity modifying protein 2-antisense RNA 1 (RAMP2-AS1), which acts as a ceRNA of miR-2355-5p to modulate the expression levels of vascular endothelial growth factor receptor 2 (VEGFR2), thus actively regulating the angiogenic ability of human umbilical vein endothelial cells (HUVECs) (15).