lnc-EGFR via regulating AP-1/NF-AT1/Foxp3 signaling pathway and lncRNA SNHG1 by regulating miR-448/IDO affect the differentiation and growth of immunosuppressive regulatory T cells (Tregs) and enable immune escape for tumor (Jiang et al., 2017; Pei et al., 2018). This evidence concerns the gene IDO1 and neoplasm.