For example, Jabandziev et al. (2014) demonstrated that specific combinations of five polymorphisms in the BPI (rs5743507), LBP (rs2232618), TLR4 (rs4986790), HSP70 (rs2227956), and IL-6 (rs1800795) genes appeared to predict the outcome of life-threatening sepsis in children. The gene discussed is TLR4; the disease is Sepsis.