CXCL8 and Sepsis: In our previous study (Gu et al., 2010), we also indicated that eight functional polymorphisms (IL1B-1470, IL1B-511, IL1B-31, IL4-589, IL6-572, IL8-251, IL10-819, and TNFA-308) could be combined together to predict the risk of sepsis and organ dysfunction after trauma.