These results demonstrate that pairing cetuximab with radiation increases MOC2-huEGFR tumor response, despite no effect of cetuximab on the viability or radiosensitivity of this tumor model (Figures 1B and 2B) and this augmented response is associated with increased tumor infiltration by both CD8+ T cells and NK cells in MOC2-huEGFR tumors. This evidence concerns the gene CD8A and neoplasm.