Protective mechanisms induced by IFN-γ have been reported during liver-stage and blood-stage infections (D’Ombrain et al., 2008; Robinson et al., 2009) with predominant sources of this cytokine being T cells and NK cells (Dodoo et al., 2002; D’Ombrain et al., 2008; Jagannathan et al., 2017). This evidence concerns the gene IFNG and infection.