NFE2L2 and brain ischemia: A study by Hsu et al. (67) found that monascin, a novel PPARγ agonist, could also activate Nrf2, and Li et al. (56) showed that luteoloside attenuated neuroinflammation in a focal cerebral ischemia model in rats by modulating the PPARγ/Nrf2/NF-κB signaling pathway.