SLC2A1 and hyperinsulinemic hypoglycemia, familial, 4: On the contrary, HRS starting in children older than 2 year of age, can guide us in addition to those formerly mentioned in the following disorders: Wilson disease (10), GLUT-1 deficiency (13), Niemann-Pick type C (12), Gaucher disease (27), manganese accumulation disorders (16, 56), glutaric aciduria type 1 (52), Celia's encephalopathy (91), gangliosidosis (26), and cerebrotendinous xanthomatosis (9).