Among the measured biomarkers, IL-6 had the highest median plasma concentration in the ALS group (10.11 pg/ml, about 8.7 times the concentration in the controls), whereas IFN-gamma has the lowest median plasma concentration in the ALS group (1.13 pg/ml, about 10.3 times the concentration in the controls) (Figure 1). The gene discussed is IFNG; the disease is amyotrophic lateral sclerosis.