In addition to its ability to be transformed into the pro-inflammatory prostaglandin E2 and leukotrienes by cyclooxygenase (COX) and 5-lipoxygenase (LO), AA can also be transformed into lipoxins, resolvins, protectins, maresins, PGE1, and PGI2, which are found to represent a series of potent bioactive compounds that have been reported to have anti-inflammatory effects in chronic liver diseases, such as ALD, NAFLD, and cirrhosis (Das, 2019). Here, CD59 is linked to metabolic dysfunction-associated steatotic liver disease.