Similarly, cancer cells undergoing ICD release the cytoplasmic protein annexin A1 (ANXA1), another DAMP that binds to formyl peptide receptor 1 (FPR1) at the surface of DCs (Vacchelli et al., 2015; Galluzzi et al., 2017; Kepp et al., 2018). The gene discussed is ANXA1; the disease is cancer.