DSP and arrhythmogenic cardiomyopathy with wooly hair and keratoderma: Autosomal dominant is the most common pattern of inheritance in AC but desmosomal recessive forms have also been reported to present a cardio-cutaneous phenotype, named Naxos disease (Kaplan et al., 2004b) when JUP carries a homozygous mutation (McKoy et al., 2000), and Carvajal syndrome when DSP carries a homozygous mutation (Carvajal-Huerta, 1998; Norgett et al., 2000).