Cortical neurons from an FTD patient carrying mutated GRN show increased vulnerability to the neurotoxin staurosporine (Almeida et al., 2012), while the affected growth of iPSC-derived cortical neurons in a separate PGRN-FTD model is rescued by the reinstatement of GRN expression (Raitano et al., 2015). The gene discussed is GRN; the disease is frontotemporal dementia.