Here, we report a novel (c.919A>C; p.Asn307His) mutation in TBC1D24 identified during WES and diagnostic panel screening of two unrelated ADHL families from Austria and the UK implying an association between AD HL disease phenotype and genetic variation affecting structural elements involved in phospholipid binding (Fischer et al., 2016). Here, TBC1D24 is linked to Hodgkins lymphoma.