TBC1D24 is a pleiotropic gene and variations cause both ARHL (DFNB86; MIM 614617), ADHL (DFNA65; MIM 616044), and several epilepsy syndromes such as AR DOORS (deafness, onychodystrophy, osteodystrophy, mental retardation, and seizures) syndrome (MIM 220500), AR early infantile epileptic encephalopathy-16 (MIM 615338) and AR familial infantile myoclonic epilepsy (MIM 605021; Mucha et al., 2017). Here, TBC1D24 is linked to DOORS syndrome.