Linear regression analysis revealed that higher sACE2 levels were significantly correlated with a higher NYHA class ≥ III, the presence of Eisenmenger physiology representing more severe CHD, a left ventricular morphology of the systemic ventricle, higher creatinine levels as well as the use of mineralocorticoid receptor antagonists (MRA) in the univariable model (Table 3). Here, NR3C2 is linked to coronary artery disorder.