TNF and neoplasm: In another case, Liu et al53 found that overexpressed hsa_circRNA_002178 could sponge miR‐328‐3p and thus up‐regulate COL1A1, which resulted in progression of breast cancer, whereas hsa_circRNA_002178 silencing could inhibit tumour inflammation by decreasing the levels of IL‐6 and TNF‐α, preventing tumour growth.