BAP1 and intrahepatic cholangiocarcinoma: For instance, recurrent mutations in isocitrate dehydrogenase (IDH)1/2, fibroblast growth factor receptor (FGFR)1‐3 and BAP1 were primarily present in ICC, whereas mutations in ARID1B, ELF3 and PRKACB occurred predominantly in ECC; the characteristics associated with the different genetic aberrations in each disease subtype contributed to its unique biological behaviour.