The four epithelial tumor clusters showed patient-specific tumor characteristics (high FGFR2 or MET) and intratumoral heterogeneity in gene expression signatures of cancer-related processes, such as cell proliferation, stemness, TGF-β signaling in EMT, hypoxia, and angiogenesis (Fig. 1e). The gene discussed is FGFR2; the disease is neoplasm.