It’s important to emphasize that further studies to comprehend the role of AURKA and AURKB modulation in mitotic cell cycle pathway and spindle control might be performed for a better understanding of AURKA and AURKB in this scenario of ALL pathogenesis, which are highly related to key activities in the pathogenesis and origin of chromosomal translocations that are the molecular signature presented in this disease43–45. This evidence concerns the gene AURKA and acute lymphoblastic leukemia.