ERCC6 and breast carcinoma: One ERCC6 SNP, rs3750751, was associated with a significantly increased risk (OR 1.35, 95% CI 1.01–1.80, p = 0.04) of breast cancer among heterozygotes in BPC3 (Table 1), and the trend (i.e., increasing number of variant alleles) was also significant (OR 1.38, 95% CI 1.05–1.81, p = 0.02).