Statistically significant increased risk of breast cancer in WHI was found with heterozygotes at ERCC6 rs1012553 (NC_000010.11:g.49532097A > T) (OR 1.35, 95% CI 1.07–1.71, p = 0.01) and rs2228528 (NC_000010.11:g.49524234C > T) (OR 1.29, 95% CI 1.01–1.66, p = 0.04) (Table 1). Here, ERCC6 is linked to breast carcinoma.