Analysis of transcriptome datasets showed statistically- significant upregulation of ERCC6 and ERCC8 in breast cancer, which is notable given the large sample size (total of 65 breast cancer samples and 153 normal tissue samples in the meta-analysis and 42 breast cancer samples and 143 normal tissue control samples in GSE10780 in individual analysis). Here, ERCC8 is linked to breast carcinoma.