There was also significant downregulation of gene expression of \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$HIF1A$$\end{document}HIF1A and FLT4 for some breast cancer co-culture conditions. This evidence concerns the gene FLT4 and breast cancer.