BSG and severe acute respiratory syndrome: CD147, known as basigin or EMMPRIN, is a transmembrane glycoprotein of the immunoglobulin superfamily,11 which participates in tumor development, Plasmodium invasion, and bacterial and virus infection.12–16 Our previous studies show that CD147 plays a functional role in facilitating SARS-CoV infection, and CD147-antagonistic peptide-9 has an inhibitory effect on SARS-CoV.17 These works affirm the importance of CD147 in virus infection for host cells.