BCL6 and diffuse large B-cell lymphoma: Another ~40% of DLBCL cases involve chromosomal translocations that lead to upregulated BCL6 expression, with breakpoints typically located in the same 5′ noncoding region60,61 (UpToDate 12, https://www.uptodate.com/contents/pathobiology-of-diffuse-large-b-cell-lymphoma-and-primary-mediastinal-large-b-cell-lymphoma).