A separate analysis of circulating tumour cells (CTCs) in the ED03 model indicate that despite the lack of any evidence of EMT in the primary xenograft tumours, the CTCs are enriched in mesenchymal gene expression, but also in epithelial genes (CDH1 and CD24), compared to the primary tumour, indicating a dysregulation of this axis and/or possibility of hybrid cells [58]. Here, CDH1 is linked to neoplasm.