Then, the miR-337-3p downregulation (Figure S1B) and GOT1 overexpression (Figure S1C) vectors were transfected into CR-NSCLC cells, and we found that the aggravating effects of hsa_circRNA_103809 ablation on cell proliferation in CR-NSCLC cells were abrogated by downregulating miR-337-3p and upregulating GOT1 (Fold changes (72 h): Cis + KD-circ+KD-miR and Cis + KD-circ+OE-GOT1 vs. Cis + KD-circ, 2.63 and 3.01 in A549/DDP; 4.32 and 4.18 in H1299/DDP cells; 2.31 and 2.19 in Calu-3/DDP. Here, GOT1 is linked to non-small cell lung carcinoma.