Furthermore, knock-down of hsa_circRNA_103809 increased cisplatin-sensitivity in CR-NSCLC cells, while overexpression of hsa_circRNA_103809 increased cisplatin-resistance in CS-NSCLC cells, which were reversed by overexpressing and silencing GOT1, suggesting that hsa_circRNA_103809 upregulated GOT1 to modulate cisplatin-resistance in NSCLC cells. Here, GOT1 is linked to non-small cell lung carcinoma.