The CCK-8 assay results indicated that upregulation of hsa_circRNA_103809 improved cell proliferation abilities in cisplatin-treated CS-NSCLC cells, which were abrogated by upregulating miR-337-3p and downregulating GOT1 (Fold changes (72 h): Cis + OE-circ+OE-miR and Cis + OE-circ+KD-GOT1 vs. Cis + OE-circ, 0.34 and 0.21 in A549; 0.21 and 0.26 in H1299; 0.43 and 0.32 in Calu-3. This evidence concerns the gene GOT1 and non-small cell lung carcinoma.