Only three variables were independently associated with cancer detection: rectal bleeding (OR 0.3, 95% CI 0.1–0.7), anemia (OR 2.8, 95% CI 1.3–5.8) and CEA > 3 ng/mL (OR 3.4, 95% CI 1.7–7.1), as shown in Table 3. Here, CEACAM5 is linked to anemia (phenotype).