SDC1 and neoplasm: In CRC cells, aberrant expression of E-cadherin/β-catenin complex can be observed as well as that of other angiogenesis markers such as Syndecan-1, platelet (Endothelial) cell adhesion molecule 1 [P(E)CAM-1, CD31], and endoglin (CD105), all involved in tumor progression and prognosis.